74-11-3 Oxidative cleavage of hydroxamic acid promoted by sodium periodate

A series of hydroxamic acids, involving aliphatic, aromatic and cyclic substrates, were transformed to the corresponding carboxylic acids through NaIO4-mediated oxidative cleavage in mild conditions. Esterification of these acids with TMSCHN2 could result in formation of the corresponding methyl ester. This methodology makes good compensation for the existing methods transforming amides to esters. Our results also pave the way to harness hydroxamic acids as useful synthetic building blocks. https://www.lookchem.com/CASDataBase_74-11-3.htm

评论

此博客中的热门博文

1023-17-2 Syntheses, structures, and catalytic activity in Friedel–Crafts acylations of substituted tetramethylcyclopentadienyl molybdenum carbonyl complexes

7440-47-3 Influence of pulse plating on the crystal structure and orientation of chromium

Competitive price of 1405-86-3 Top quality of Glycyrrhizic acid A exporter