1769-24-0 Facile and solvent-free synthesis of quinazolin-4(3H)-ones under microwave condition promoted by SbCl3

– Antimony trichloride (SbCl3) was found to be an effective catalyst (1 mol%) for one-pot synthesis of quinazolin-4(3H)-ones in good to excellent yields using anthranilamide and acyl chlorides under microwave irradiation. This method has the advantages of simplicity, mild reaction conditions, highly tolerant to several functional groups, as well as the avoidance of hazardous solvents. https://www.lookchem.com/CASDataBase_1769-24-0.htm

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